Cancer BiologybioRxivPreprint
Iron and lipocalin-2 modulate cellular responses in the tumor micro-environment of pancreatic ductal adenocarcinoma
V. Pita-Grisanti, A. W. Dangel, K. Gumpper…·Z. Cruz-Monserrate
This study shows that iron and lipocalin-2 (LCN2) influence PDAC cell behavior and metastasis, with LCN2 deletion reducing metastasis and iron chelation increasing anti-metastatic gene expression.
DOI 10.1101/2020.01.14.907188