NELL-1 regulates the matrisome to alter osteosarcoma disease progression
Q. Qin, M. Gomez-Salazar, R. J. Tower, L. Chang, C. D. Morris, E. F. McCarthy, K. Ting, X. Zhang, A. W. James
This study shows NELL-1 promotes osteosarcoma progression by altering the matrisome, with loss of NELL-1 reducing invasion and improving survival in both human and mouse models.
bioRxiv · Jan 21, 2022 · PreprintCancer Biology