Author

A. W. Middleton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Lindqvist· 2 shared E. Mullers· 1 shared H. Silva Cascales· 1 shared H. Stoy· 1 shared K. Akopyan· 1 shared K. Burdova· 1 shared L. Baranello· 1 shared L. Macurek· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

A. Lindqvist

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2 papers

Recent·Most cited

Cell BiologybioRxivJul 29, 2020

Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate Plk1

H. Silva Cascales, K. Burdova, A. W. Middleton…·A. Lindqvist

This study shows Cyclin A2 localizes to the cytoplasm at the S/G2 transition to activate PLK1 by interacting with Bora, and this cytoplasmic presence is restricted by p21.

DOI 10.26508/lsa.202000980

humanproteomics

𝕏 PostBluesky

Cell BiologybioRxivPreprintJun 9, 2020

p53-dependent polyploidisation after DNA damage in G2 phase

A. W. Middleton, R. Suman, P. O'Toole…·A. Lindqvist

This study shows that G2 phase cell cycle exit in p53-positive cells can lead to polyploidisation through repeated DNA re-replication rather than senescence.

DOI 10.1101/2020.06.09.141770

humanexperimental assay

𝕏 PostBluesky