Author

E. Mullers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. Bender· 1 shared A. Lindqvist· 1 shared A. Martinsson· 1 shared A. W. Middleton· 1 shared B. Casas· 1 shared C. Ammala· 1 shared C. Wennberg Huldt· 1 shared E. Mouchet· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Bender

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Diseased human pancreas and liver microphysiological system for preclinical diabetes research

S. Rigal, B. Casas, K. P. Kanebratt, C. Wennberg Huldt, L. U. Magnusson, E. Mullers, F. Kalrsson, M. Clausen, S. F. Hansson, R. Jansson Lofmark, C. Ammala, U. Marx, P. Gennemark, G. Cedersund, T. B. Andersson, L. K. Vilen

This paper develops a microphysiological system combining pancreas and liver to study diabetes, showing disease phenotypes and therapeutic potential.

bioRxiv · Jul 3, 2023 · PreprintCell Biology

Cell morphological profiling enables high-throughput screening for PROteolysis TArgeting Chimera (PROTAC) phenotypic signature

K. Moreau, M.-A. Trapotsi, E. Mouchet, G. Williams, T. Monteverde, K. Juhani, R. Turkki, F. Miljkovic, A. Martinsson, L. Mervin, E. Mullers, I. Barrett, O. Engkvist, A. Bender

This study uses cell morphological profiling to identify phenotypic signatures of PROTACs, revealing mitotoxicity that cannot be predicted from individual components.

bioRxiv · Jan 17, 2022Pharmacology & Toxicology

Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate Plk1

H. Silva Cascales, K. Burdova, A. W. Middleton, V. Kuzin, E. Mullers, H. Stoy, L. Baranello, L. Macurek, A. Lindqvist

This study shows Cyclin A2 localizes to the cytoplasm at the S/G2 transition to activate PLK1 by interacting with Bora, and this cytoplasmic presence is restricted by p21.

bioRxiv · Jul 29, 2020Cell Biology