ImmunologyCell Reports MedicinePeer-reviewed
Selective refueling of CAR T cells using ADA1 and 1 CD26 boosts antitumor immunity
Yue Hu, Abhijit Sarkar, Kevin Song…·Xiao‐Tong Song
This study shows that engineering CAR T cells to co-express ADA1 and CD26 improves their antitumor activity by selectively refueling them with inosine in the tumor microenvironment.
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