Author

Abhinav K. Jain

The University of Texas MD Anderson Cancer Center

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Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Akata SahaiD· 1 shared Alexander S. ShavkunoviD· 1 shared Avery J. SalmoniD· 1 shared Brian T. EdelsoniD· 1 shared Ken CheniD· 1 shared Kenneth H. HuiD· 1 shared Kristen E. PaukeniD· 1 shared Kunal RaiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Akata SahaORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintOct 10, 2025

Bhlhe40 Governs T Cell Effector Differentiation with Distinct Requirements in CD4 and CD8 T Cells for Anti-PD-1 and Anti-CTLA-4 Efficacy

Akata Saha, Tomoyuki Minowa, Alexander S. Shavkunov…·Matthew M. Gubin

This study identifies Bhlhe40 as a key regulator of T cell effector differentiation, showing distinct roles in CD4 and CD8 T cells for anti-PD-1 and anti-CTLA-4 therapies.

DOI 10.1101/2025.10.10.681497

mousebulk RNA-seq

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