ImmunologyNature CommunicationsPeer-reviewed
LSD1 inhibition improves efficacy of adoptive T cell therapy by enhancing CD8+ T cell responsiveness.
Isabella Pallavicini, Teresa Maria Frasconi, Carlotta Catozzi…·Teresa Manzo
This study shows that inhibiting LSD1 enhances CD8+ T cell function in adoptive T cell therapy, leading to improved antitumor immunity and synergistic effects with anti-PDL1 therapy.