Author

Teresa Manzo

University of MilanORCID 0000-0001-8552-3625Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CITE-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Carina B. Nava LausoniD· 2 shared Carlotta CatozziiD· 2 shared Luigi NeziiD· 2 shared Silvia TibertiiD· 2 shared Alberto Bigogno· 1 shared Alessia LoffredaiD· 1 shared Christoph Heuser-LoyiD· 1 shared Ciro MercurioiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Carina B. Nava LausonORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 9, 2025

Palmitate-induced mitochondrial damage restricts histone acetylation in CD8+ T cells to impair anti-tumor immunity.

Silvia Tiberti, Martina Romeo, Letizia Rumiano…·Teresa Manzo

This study shows that palmitate impairs CD8+ T cell function by damaging mitochondria and reducing histone acetylation, leading to weakened anti-tumor immunity.

DOI 10.1101/2025.01.09.631811

humanbulk RNA-seq

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ImmunologyNature CommunicationsPeer-reviewedAug 27, 2024

LSD1 inhibition improves efficacy of adoptive T cell therapy by enhancing CD8+ T cell responsiveness.

Isabella Pallavicini, Teresa Maria Frasconi, Carlotta Catozzi…·Teresa Manzo

This study shows that inhibiting LSD1 enhances CD8+ T cell function in adoptive T cell therapy, leading to improved antitumor immunity and synergistic effects with anti-PDL1 therapy.

22 citations

mouseCITE-seq

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