Cancer BiologybioRxivPreprint
Cholesterol deprivation induces TGFβ signaling to promote basal differentiation in pancreatic cancer
Linara G. Cornell, Suraj Peri, Diana Restifo…·Igor Astsaturov
The paper shows that cholesterol deprivation activates TGFβ signaling, promoting basal differentiation in pancreatic cancer by stabilizing the TGFβ receptor.