Evaluation of Candidate ''Kill or Cure'' Strategies to Treat MFN2-related Lipodystrophy
Ineke H. N. Luijten, Xiong Weng, Ula Kibildyte…·Robert K. Semple
This study evaluates 'kill or cure' strategies for MFN2-related lipodystrophy, finding that ethanol mildly worsens the condition in mice while rapamycin is well-tolerated but lacks efficacy in targeting Mfn2R707W cells.