ImmunologybioRxiv
IL-7R signalling activates widespread VH and DH gene usage to drive antibody diversity in bone marrow B cells
A. Baizan Edge, B. A. Stubbs, M. J. T. Stubbington…·A. E. Corcoran
This study shows IL-7R signalling influences VH and DH gene usage in bone marrow B cells, shaping the Igh repertoire through epigenetic mechanisms.
DOI 10.1016/j.celrep.2021.109349