Suppression of epithelial proliferation and tumorigenesis by immunoglobulin A
G. P. Donaldson, G. L. Reis, M. Saad, C. Wichmann, I. Mamede, G. Chen, C. E. Harrer, N. L. DelGaudio, D. Zhang, B. Aydin, T. B. R. Castro, S. Grivennikov, B. S. Reis, E. Liu, S. C. Eisenbarth, , D. Mucida
This study shows that IgA suppresses epithelial proliferation and tumorigenesis by interacting with DMBT1, highlighting its role in maintaining mucosal homeostasis.
bioRxiv · Oct 6, 2023 · PreprintImmunology