Author

B. Brook

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1

Frequent Co-Authors

D. J. Dowling· 2 shared E. Nanishi· 2 shared F. Borriello· 2 shared M. De Leon· 2 shared M. Menon· 2 shared O. Levy· 2 shared S. D. van Haren· 2 shared Y. Saito· 2 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

D. J. Dowling

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2 papers

Recent·Most cited

Shaping neonatal immunization by tuning delivery of synergistic adjuvants via nanocarriers

S. Barman, F. Borriello, B. Brook, C. Pietrasanta, M. De Leon, C. Sweitzer, M. Menon, S. D. van Haren, D. Soni, Y. Saito, E. Nanishi, S. Yi, S. Bobbala, O. Levy, E. A. Scott, D. J. Dowling

This study identifies synergistic adjuvants for neonatal immunization using nanocarriers, showing enhanced Th1 bias and humoral responses in mice.

bioRxiv · Jun 3, 2022Immunology

Alum:CpG adjuvant enables SARS-CoV-2 RBD-induced protection in aged mice and synergistic activation of human elder type 1 immunity

E. Nanishi, F. Borriello, T. R. O'Meara, M. E. McGrath, Y. Saito, R. E. Haupt, H.-S. Seo, S. D. van Haren, B. Brook, J. Chen, J. Diray-Arce, S. Doss-Gollin, M. De Leon, K. Chew, M. Menon, , D. J. Dowling

This study evaluates AH:CpG adjuvant's ability to enhance RBD vaccine efficacy in aged mice and human elder cells, showing strong neutralizing antibody responses and cytokine production.

bioRxiv · May 20, 2021Immunology