Author

B. D. Walker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 6 Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Piechocka-Trocha· 2 shared N. Ismail· 2 shared T. Ndung'u· 2 shared Z. M. Ndhlovu· 2 shared A. K. Shalek· 1 shared A. Magnuson· 1 shared A. Moodley· 1 shared A. P. West· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersImmunology

A. Piechocka-Trocha

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Author profile →

6 papers

Recent·Most cited

A naturally arising broad and potent CD4-binding site antibody with low somatic mutation

C. O. Barnes, T. Schoofs, P. N. P. Gnanapragasam, J. Golijanin, K. E. Huey-Tubman, H. Gruell, P. Schommers, N. Suh-Toma, Y. E. Lee, J. C. C. Lorenzi, A. Piechocka-Trocha, J. F. Scheid, A. P. West, B. D. Walker, M. S. Seaman, , P. J. Bjorkman

This paper describes a VRC01-class antibody with lower somatic mutation but comparable breadth and potency to other broadly neutralizing antibodies against HIV-1.

bioRxiv · Mar 16, 2022Immunology

HIV proviral burden, genetic diversity and dynamics in viremic controllers who subsequently initiated suppressive antiretroviral therapy

F. H. Omondi, H. Sudderuddin, A. Shahid, N. N. Kinloch, B. R. Jones, R. L. Miller, O. Tsai, D. MacMillan, A. Trocha, M. A. Brockman, C. J. Brumme, J. B. Joy, R. Liang, B. D. Walker, Z. L. Brumme

This study characterizes proviral burden, diversity, and dynamics in viremic controllers before and after ART initiation using phylogenetic analysis and mathematical modeling.

bioRxiv · Mar 29, 2021Microbiology

Profound Treg perturbations correlate with COVID-19 severity

S. Galvan-Pena, J. Leon, K. Chowdhary, D. A. Michelson, B. Vijaykumar, L. Yang, A. Magnuson, Z. Manickas-Hill, A. Piechocka-Trocha, D. P. Worrall, K. E. Hall, M. Ghebremichael, B. D. Walker, J. Z. Li, X. G. Yu, , C. Benoist

The paper identifies Treg cell perturbations in severe COVID-19 patients, showing increased FoxP3 levels and pro-inflammatory traits linked to disease severity.

bioRxiv · Dec 11, 2020Immunology

Dendritic cells focus CTL responses toward highly conserved and topologically important HIV epitopes

T. M. Garcia-Bates, M. L. Palma, D. C. HSU, J. Ananworanich, B. T. Korber, G. D. Gaiha, N. Phanuphak, R. Thomas, S. Tovanabutra, B. D. Walker, J. W. Mellors, P. A. Piazza, E. Kroon, S. A. Riddler, N. L. Michael, , R. B. Mailliard

This study uses dendritic cells to focus CD8+ T cell responses on conserved and topologically important HIV epitopes to prevent immune escape.

bioRxiv · Jul 13, 2020Immunology

Integrated Single-Cell Analysis of Multicellular Immune Dynamics during Hyper-Acute HIV-1 Infection

S. W. Kazer, T. P. Aicher, D. M. Muema, S. L. Carroll, J. Ordovas-Montanes, C. G. K. Ziegler, S. K. Nyquist, E. B. Wong, N. Ismail, M. Dong, A. Moodley, K. L. Dong, Z. M. Ndhlovu, T. Ndung'u, B. D. Walker, A. K. Shalek

The paper uses single-cell RNA-sequencing to study immune dynamics in HIV-1 infection, identifying key cellular responses and their temporal progression in untreated individuals.

bioRxiv · May 30, 2019 · PreprintImmunology

Frequencies of circulating Th1-biased T follicular helper cells in acute HIV-1 infection correlate with the development of HIV-specific antibody responses and lower set point viral load

O. Baiyegunhi, B. Ndlovu, F. Ogunshola, N. Ismail, B. D. Walker, T. Ndung'u, Z. M. Ndhlovu

This study shows that higher frequencies of Tfh1 cells during acute HIV-1 infection correlate with stronger antibody responses and lower viral load.

bioRxiv · Apr 20, 2018Immunology