Author

J. Ananworanich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:CUT&Tag· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

N. Phanuphak· 4 shared D. Hsu· 3 shared E. Kroon· 3 shared M. L. Robb· 3 shared S. Tovanabutra· 3 shared S. Vasan· 3 shared A. Schuetz· 2 shared C. Sacdalan· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersMicrobiology

N. Phanuphak

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Tracking coreceptor switch of the transmitted/founder HIV-1 identifies co-evolution of HIV-1 antigenicity, coreceptor usage and CD4 subset targeting

M. H. Marichannegowda, M. Zemil, L. Wieczorek, E. Sanders-Buell, M. Bose, A. M. O'Sullivan, D. King, L. Francisco, F. Diaz-Mendez, S. Setua, N. Chomont, N. Phanuphak, J. Ananworanich, D. Hsu, S. Vasan, , H. Song

The paper tracks the coreceptor switch of HIV-1 in early infection, finding that a single mutation can drive X4 variants and co-evolution of antigenicity and tropism.

bioRxiv · Jan 21, 2023 · PreprintMicrobiology

Productive and latent HIV infections originate in resting CD4+ T cells

S. Wietgrefe, J. Anderson, L. Duan, P. J. Southern, P. Zuck, G. Wu, B. Howell, C. Reilly, E. Kroon, S. Chottanapund, S. Buranapraditkun, C. Sacdalan, N. Tulmethakaan, D. J. Colby, N. Chomchey, , A. T. Haase

This study shows that resting CD4+ T cells are the initial source of both productive and latent HIV infections in the earliest stages of detectable infection.

bioRxiv · Aug 26, 2022 · PreprintImmunology

HIV rapidly targets a diverse pool of CD4+ T cells to establish productive and latent infections

P. Gantner, S. Buranapraditkun, A. Pagliuzza, C. Dufour, M. Pardons, J. L. Mitchell, E. Kroon, C. Sacdalan, N. Tulmethakaan, S. Pinyakorn, M. L. Robb, N. Phanuphak, J. Ananworanich, D. Hsu, S. Vasan, , N. Chomont

This study identifies that HIV initially infects diverse CD4+ T cells in blood and lymph nodes, establishing both productive infections and latent reservoirs simultaneously.

bioRxiv · May 10, 2022Microbiology

Dendritic cells focus CTL responses toward highly conserved and topologically important HIV epitopes

T. M. Garcia-Bates, M. L. Palma, D. C. HSU, J. Ananworanich, B. T. Korber, G. D. Gaiha, N. Phanuphak, R. Thomas, S. Tovanabutra, B. D. Walker, J. W. Mellors, P. A. Piazza, E. Kroon, S. A. Riddler, N. L. Michael, , R. B. Mailliard

This study uses dendritic cells to focus CD8+ T cell responses on conserved and topologically important HIV epitopes to prevent immune escape.

bioRxiv · Jul 13, 2020Immunology

Monocyte Infection Dynamics Shape HIV-1 Phyloanatomy in the Peripheral Blood

B. Rife Magalis, S. L. Strickland, S. D. Shank, P. Autissier, A. Schuetz, P. Sithinamsuwam, S. Lerdlum, J. L. K. Fletcher, M. de Souza, J. Ananworanich, V. Valcour, K. C. Williams, S. L. Kosakovsky Pond, S. Ratto Kim, M. Salemi, SEARCH007

This study shows that HIV-1 evolves differently in monocytes compared to T cells, suggesting monocytes may be a significant viral reservoir.

bioRxiv · Dec 12, 2018 · PreprintEvolutionary Biology