B. E. Vos

Intracellular mechanical fingerprint reveals cell type-specific mechanical differences

The paper defines a mechanical fingerprint to characterize intracellular mechanical states and reveals cell type-specific differences related to biological function.

Primordial germ cells adjust their protrusion type while migrating in different tissue contexts in vivo

This study shows zebrafish primordial germ cells change their protrusion type and blebbing behavior depending on the tissue environment, maintaining motility parameters through adjustments in RhoA activity and cortical tension.

Pressure drives rapid burst-like collective migration from 3D cancer aggregates

The paper demonstrates that pressure differences inside 3D cancer aggregates drive rapid burst-like collective migration in HeLa cells, independent of ECM pulling forces.

Designing a high-resolution, LEGO-based microscope for an educational setting

The paper designs a low-cost, LEGO-based microscope for educational use, showing it can resolve micrometer-sized objects and improve student understanding of microscopy.

Intracellular softening and fluidification reveals a mechanical switch of cytoskeletal material contributions during division

The paper shows that during cell division, the cytoplasm softens and fluidifies, with microtubules and actin switching roles in controlling mechanical properties.

Molecular packing structure of fibrin fibers resolved by X-ray scattering and molecular modeling

This study resolves the molecular packing structure of fibrin fibers using X-ray scattering and molecular modeling, revealing key structural features that explain their mechanical properties.

Revealing the molecular origins of fibrin’s elastomeric properties by in situ X-ray scattering

This study uses in situ X-ray scattering to reveal how fibrin's molecular structure contributes to its extensibility under shear strain, showing that fiber elongation arises from uncoiling of disordered C-peptide linkers.

Automated Tracking of Biopolymer Growth and Network Deformation with TSOAX

The paper introduces an open-source software tool for automated tracking of biopolymer networks in 2D and 3D using stretching open active contours, demonstrating its application in live cell studies.