Author

B. Engelhardt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

S. Aydin· 2 shared U. Deutsch· 2 shared A. Ariga· 1 shared A. Ben-Zvi· 1 shared A. Johnson· 1 shared A. Klopstein· 1 shared A. Mossu· 1 shared A. Pal· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

S. Aydin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

UFMTrack: Under-Flow Migration Tracker enabling analysis of the entire multi-step immune cell extravasation cascade across the blood-brain barrier in microfluidic devices

M. Vladymyrov, L. Marchetti, S. Aydin, S. G. N. Soldati, A. Mossu, A. Pal, L. Gueissaz, A. Ariga, B. Engelhardt

UFMTrack automates analysis of immune cell extravasation across the BBB in microfluidic devices, achieving 90% track reconstruction efficiency and reducing experimenter bias.

bioRxiv · Jan 4, 2023Immunology

The Modular μSiM: a Mass Produced, Rapidly Assembled, and Reconfigurable Platform for the Study of Barrier Tissue Models In Vitro

M. C. McCloskey, P. Kasap, S. D. Ahmad, S.-H. Su, K. Chen, M. Mansouri, N. Ramesh, H. Nishihara, Y. Belyaev, V. V. Abhyankar, S. Begolo, B. H. Singer, K. F. Webb, K. Kurabayashi, J. Flax, , J. L. McGrath

The paper introduces a modular, mass-produced tissue chip platform for barrier tissue models, validated for blood-brain barrier studies and reconfigurable for other applications.

bioRxiv · Mar 28, 2022Bioengineering

Brain endothelial antigen presentation detains CD8+ T cells at the blood-brain barrier leading to its breakdown

S. Aydin, J. Pareja, V. M. Schallenberg, A. Klopstein, T. Gruber, N. Page, E. Kaba, U. Deutsch, A. Johnson, M. Schenk, D. Merkler, B. Engelhardt

The paper shows that brain endothelial antigen presentation inhibits CD8+ T-cell movement and causes BBB breakdown in MS.

bioRxiv · Oct 12, 2021 · PreprintImmunology

Nano-scale Architecture of Blood-Brain Barrier Tight-Junctions

E. Sasson, S. Anzi, B. Bell, O. Yakovian, M. Zorsky, U. Deutsch, B. Engelhardt, E. Sherman, G. D. Vatine, R. Dzikowski, A. Ben-Zvi

This study uses super-resolution microscopy to reveal the nano-scale molecular architecture of BBB tight junctions and their developmental maturation process.

bioRxiv · Aug 12, 2021Cell Biology