Author

S. Aydin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

B. Engelhardt· 2 shared A. Ariga· 1 shared A. Johnson· 1 shared A. Klopstein· 1 shared A. Loriot· 1 shared A. Mossu· 1 shared A. Pal· 1 shared C. Hubert· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

B. Engelhardt

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Spatial transcriptomics profiling of gallbladder adenocarcinoma: a detailed two-case study of progression from precursor lesions to cancer

S. Pirenne, F. Manzano-Nunez, A. Loriot, S. Cordi, L. Desmet, S. Aydin, C. Hubert, S. Toffoli, N. Limaye, C. Sempoux, M. Komuta, L. Gatto, F. P. Lemaigre

This study uses spatial transcriptomics to analyze two gallbladder cancer patients, showing distinct progression paths and the role of SEMA4A repression in tumor development.

bioRxiv · Feb 27, 2024Cancer Biology

UFMTrack: Under-Flow Migration Tracker enabling analysis of the entire multi-step immune cell extravasation cascade across the blood-brain barrier in microfluidic devices

M. Vladymyrov, L. Marchetti, S. Aydin, S. G. N. Soldati, A. Mossu, A. Pal, L. Gueissaz, A. Ariga, B. Engelhardt

UFMTrack automates analysis of immune cell extravasation across the BBB in microfluidic devices, achieving 90% track reconstruction efficiency and reducing experimenter bias.

bioRxiv · Jan 4, 2023Immunology

Brain endothelial antigen presentation detains CD8+ T cells at the blood-brain barrier leading to its breakdown

S. Aydin, J. Pareja, V. M. Schallenberg, A. Klopstein, T. Gruber, N. Page, E. Kaba, U. Deutsch, A. Johnson, M. Schenk, D. Merkler, B. Engelhardt

The paper shows that brain endothelial antigen presentation inhibits CD8+ T-cell movement and causes BBB breakdown in MS.

bioRxiv · Oct 12, 2021 · PreprintImmunology