Author

G. Perona-Wright

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:cell signaling & trafficking· 4 Research Focus:host-pathogen & immune response· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Assay:flow cytometry· 2 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. T. Andrusaite· 2 shared G. A. Heieis· 2 shared H. C. Webster· 2 shared R. M. Maizels· 2 shared S. W. F. Milling· 2 shared A. Cooper· 1 shared A. Girard· 1 shared A. L. Shergold· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

A. T. Andrusaite

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Author profile →

5 papers

Recent·Most cited

A PD-1-ST2 axis controls Th2 effector function in tissue via a metabolic checkpoint

G. A. Heieis, B. Everts, C. W. Roberts, R. M. Maizels, G. Perona-Wright

This study shows that PD-1 signaling regulates Th2 cell metabolism and IL-33 receptor expression through fatty acid oxidation, suggesting PD-1 blockade could treat Th2-related diseases.

bioRxiv · Aug 13, 2023 · PreprintImmunology

IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic Trypanosoma brucei infection

M. C. Sinton, P. Chandrasegaran, P. Capewell, A. Cooper, A. Girard, J. Ogunsola, G. Perona-Wright, D. Ngoyi, N. Kuispond, B. BUCHETON, M. Camara, S. Kajimura, C. Benezech, A. MacLeod, J. F. Quintana Alcala

bioRxiv · Sep 23, 2022Immunology

Tissue-based IL-10 signalling in helminth infection limits IFNγ expression and promotes the intestinal Th2 response

H. C. Webster, V. Gamino, A. L. Shergold, A. T. Andrusaite, G. A. Heieis, S. W. F. Milling, R. M. Maizels, G. Perona-Wright

This study shows IL-10 promotes Th2 responses and suppresses IFNγ in intestinal helminth infection by regulating Th1 cells.

bioRxiv · Aug 10, 2021Immunology

Recruited macrophages that colonise the post-inflammatory peritoneal niche convert into functionally divergent resident cells

P. A. Louwe, L. Badiola-Gomez, H. Webster, G. Perona-Wright, C. C. Bain, S. J. Forbes, S. J. Jenkins

This study shows inflammation-elicited macrophages in the peritoneal cavity can adopt a resident-like identity but are functionally divergent due to environmental influences and time of residency.

bioRxiv · Nov 30, 2020Immunology

Isolation and functional characterisation of lamina propria leukocytes from helminth-infected, murine small intestine

H. C. Webster, A. T. Andrusaite, S. W. F. Milling, G. Perona-Wright

This study develops an optimized protocol to isolate lamina propria leukocytes from helminth-infected mice and characterizes myeloid and CD4+ T cell subsets.

bioRxiv · Aug 29, 2019Immunology