Author

B. Kalfaoglu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

J. Almeida-Santos· 3 shared M. Ono· 3 shared C. A. Tye· 2 shared J. Hassan· 2 shared Y. Satou· 2 shared A. Melcher· 1 shared B. J. Y. Tan· 1 shared E. Appleton· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersImmunology

J. Almeida-Santos

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Author profile →

3 papers

Recent·Most cited

Temporal profiling of CD4 T-cell activation and differentiation upon SARS-CoV-2 spike protein immunisation

J. Almeida-Santos, R. Berkachy, C. A. Tye, J. Hassan, B. Kalfaoglu, M. E. Selkirk, M. Ono

This study investigates how TCR signaling controls CD4 T-cell differentiation and Treg development after SARS-CoV-2 spike protein immunization using temporal profiling techniques.

bioRxiv · Jul 21, 2022 · PreprintImmunology

Single-cell level temporal profiling of tumour-reactive T cells under immune checkpoint blockade

J. Hassan, E. Appleton, B. Kalfaoglu, M. Pedersen, J. Almeida-Santos, H. Kanemaru, N. Irie, S. Foo, O. Reda, B. J. Y. Tan, I.-m. Okazaki, T. Okazaki, Y. Satou, K. Harrington, A. Melcher, M. Ono

This study uses a novel mouse model to analyze how checkpoint blockade affects tumour-reactive T cell activation dynamics at the single-cell level.

bioRxiv · Jul 19, 2022 · PreprintImmunology

T-cell hyperactivation and paralysis in severe COVID-19 infection revealed by single-cell analysis

B. Kalfaoglu, J. Almeida-Santos, C. A. Tye, Y. Satou, M. Ono

This study identifies hyperactivation and paralysis of CD4+ T-cells in severe COVID-19 through single-cell analysis, revealing their role in cytokine release syndrome and viral entry.

bioRxiv · May 26, 2020Immunology