Author

O. Reda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:proteomics· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

B. J. Y. Tan· 4 shared Y. Satou· 4 shared K. Sugata· 3 shared M. Ono· 3 shared A. Utsunomiya· 2 shared M. Tokunaga· 2 shared A. Melcher· 1 shared A. Rahman· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersImmunology

B. J. Y. Tan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Viral antigen mismatch affects antiviral T-cell response and may impair immunotherapeutic efficacy against ATL

K. Sugata, M. Takatori, O. Reda, B. J. Y. Tan, M. Tokunaga, T. Sato, M. Ueda, Y. Yamano, A. Utsunomiya, Y. Satou

This study shows that mismatch between viral antigen epitopes and T-cell responses in HTLV-1 infection may reduce immunotherapy effectiveness against ATL.

bioRxiv · Jan 25, 2024 · PreprintImmunology

HIV-Tocky system to visualize proviral expression dynamics

O. Reda, K. Monde, K. Sugata, A. Rahman, W. Sakhor, S. A. Rajib, S. N. Sithi, B. J. Y. Tan, K. Niimura, C. Motozono, K. Maeda, M. Ono, H. Takeuchi, Y. Satou

The paper introduces HIV-Tocky, a reporter system using a fluorescent Timer protein to visualize HIV-1 provirus expression dynamics and identifies two latent subsets of proviruses.

bioRxiv · Aug 10, 2023Microbiology

Single-cell level temporal profiling of tumour-reactive T cells under immune checkpoint blockade

J. Hassan, E. Appleton, B. Kalfaoglu, M. Pedersen, J. Almeida-Santos, H. Kanemaru, N. Irie, S. Foo, O. Reda, B. J. Y. Tan, I.-m. Okazaki, T. Okazaki, Y. Satou, K. Harrington, A. Melcher, M. Ono

This study uses a novel mouse model to analyze how checkpoint blockade affects tumour-reactive T cell activation dynamics at the single-cell level.

bioRxiv · Jul 19, 2022 · PreprintImmunology

Retrovirus-induced leukemia - hijack of T-cell activation mechanisms revealed by single-cell analysis

B. J. Y. Tan, K. Sugata, O. Reda, M. Matsuo, K. Uchiyama, P. Miyazato, V. Hahaut, M. Yamagishi, K. Uchimaru, Y. Suzuki, T. Ueno, H. Suzushima, H. Katsuya, M. Tokunaga, Y. Uchiyama, , Y. Satou

This study uses single-cell RNA-Seq and TCR-Seq to show HTLV-1-infected T-cells transition into highly activated ATL cells with Treg signatures and upregulated HLA class II, enabling immune evasion.

bioRxiv · Sep 1, 2021 · PreprintMicrobiology