Author

B. Larijani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Acha-Sagredo· 1 shared C. Swanton· 1 shared D. Temelkovski· 1 shared E. Fontana· 1 shared E. Nye· 1 shared F. D. Ciccarelli· 1 shared G. A. Wilson· 1 shared G. De Las Heras· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Acha-Sagredo

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Immunogenomic profile of colorectal cancer response to immune checkpoint blockade

M. Bortolomeazzi, M. R. Keddar, L. Montorsi, A. Acha-Sagredo, L. Benedetti, D. Temelkovski, S. Choi, N. Petrov, K. Todd, P. Wai, J. Kohl, T. Denner, E. Nye, R. Goldstone, S. Ward, , F. D. Ciccarelli

This study identifies immunogenomic features predicting response to immune checkpoint blockade in colorectal cancer, showing that high clonality and immune escape mechanisms are more important than mutational burden.

bioRxiv · Dec 15, 2020 · PreprintCancer Biology

A Complex Interplay of Anionic Phospholipid Binding Regulates 3-Phosphoinositide-Dependent-Kinase-1 Homodimer Activation

G. De Las Heras, V. Calleja, R. Bailly, J. Dessolin, J. Requejo-Isidro, B. Larijani

This study reveals how anionic phospholipids regulate PDK1 homodimer activation through conformational dynamics, showing phosphatidylserine maintains inactivity and dysregulation leads to constitutive activation in carcinomas.

bioRxiv · Mar 3, 2019Biophysics