Author

K. Todd

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Assay:spatial transcriptomics· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. Spencer· 3 shared L. Montorsi· 3 shared N. Petrov· 2 shared A. Acha-Sagredo· 1 shared A. Green· 1 shared B. Larijani· 1 shared C. Armitage· 1 shared C. Bishop· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersImmunology

J. Spencer

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Type-2 diabetes mellitus enhances Klebsiella pneumoniae pathogenesis

K. Todd, K. Gunter, J. M. Bowen, C. L. Holmes, N. L. Tilston-Lunel, J. Vornhagen

This study shows that type 2 diabetes mellitus enhances Klebsiella pneumoniae pathogenesis by increasing gut colonization and lung infection severity.

bioRxiv · May 31, 2024 · PreprintMicrobiology

Disrupted Peyer's patch microanatomy in COVID-19 including germinal centre atrophy independent of local virus

S. C. Trevelin, S. Pickering, K. Todd, C. Bishop, M. Pitcher, J. G. Mesa, L. Montorsi, F. Spada, N. Petrov, A. Green, M. Shankar-Hari, S. J. D. Neil, J. Spencer

This study examines the impact of COVID-19 on ileal Peyer's patches, finding disrupted microanatomy and germinal centre atrophy independent of local viral load.

bioRxiv · Dec 17, 2021Immunology

Two subsets of human marginal zone B cells resolved by global analysis of lymphoid tissues and blood

J. H. Siu, M. J. Pitcher, T. J. Tull, W. Guesdon, L. Montorsi, C. Armitage, K. T. Mahbubani, R. Ellis, P. Dhami, K. Todd, U. D. Kadolsky, M. Kleeman, D. P. D'Cruz, K. Saeb-Parsy, M. Bemark, , J. Spencer

The paper identifies two distinct subsets of human marginal zone B cells through global analysis of lymphoid tissues and blood, revealing differences in their biology and distribution.

bioRxiv · Mar 19, 2021Immunology

Immunogenomic profile of colorectal cancer response to immune checkpoint blockade

M. Bortolomeazzi, M. R. Keddar, L. Montorsi, A. Acha-Sagredo, L. Benedetti, D. Temelkovski, S. Choi, N. Petrov, K. Todd, P. Wai, J. Kohl, T. Denner, E. Nye, R. Goldstone, S. Ward, , F. D. Ciccarelli

This study identifies immunogenomic features predicting response to immune checkpoint blockade in colorectal cancer, showing that high clonality and immune escape mechanisms are more important than mutational burden.

bioRxiv · Dec 15, 2020 · PreprintCancer Biology