Post-translational regulation of Platelet-derived growth factor receptor β is critical for fracture repair in aged mice
J. Tao, B. Lipe, B. Boyce, L. Xing, H. ZHANG
This study identifies PDGFRβ as a target of proteasome inhibitors in aged mice, showing that its degradation impairs fracture repair and that combined PDGF-BB and proteasome inhibitor treatment improves repair.
bioRxiv · Nov 4, 2023 · PreprintCell Biology