B. Lopez

Skin Sensitisation Case Study: Comparison of Defined Approaches including OECD 497 Guidance

The paper compares different defined approaches for skin sensitisation assessment, including OECD guidance and emerging methods, to evaluate their effectiveness in characterising chemical compounds.

Dendritic cell-Natural Killer cell Crosstalk Modulates T cell activation in Response to Influenza A Viral Infection

This study shows that influenza A virus infection impairs dendritic cell-NK cell crosstalk, reducing T cell activation in an ex vivo human immune cell culture system.

Human RAD52 stimulates the RAD51-mediated homology search

This study investigates the role of RAD52 in homologous recombination by analyzing its interaction with BRCA2 and RAD51 using electron microscopy and biochemistry.

Peptidome profiling for the immunological stratification in sepsis: a proof of concept study

This study uses plasma peptidome profiling with MALDI-TOF mass spectrometry and machine learning to stratify sepsis phases in mice, achieving high sensitivity and specificity.

Mycobacterium tuberculosis Modulates the Metabolism of Alternatively Activated Macrophages to Promote Foam Cell Formation and Intracellular Survival

This study shows that Mtb modulates macrophage metabolism to promote foam cell formation and survival by altering lipid metabolism and FAO pathways.

Frequent Monitoring of C-peptide Levels in Newly Diagnosed Type 1 Subjects Using Dried Blood Spots Collected at Home

This study evaluates a method for frequent C-peptide monitoring at home using dried blood spots in newly diagnosed type 1 diabetes patients, showing strong correlation with plasma levels and potential for tracking beta-cell function changes.