Author

B. M. Peterlin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

F. Huang· 2 shared K. Fujinaga· 2 shared A. Sali· 1 shared A. Weiss· 1 shared D. A. Frabutt· 1 shared D. C. Cary· 1 shared H. Paculova· 1 shared I. Ahmad· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiochemistry

F. Huang

Mutual co-authors in cluster

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3 papers

Recent·Most cited

P-TEFb is degraded by Siah1/2 in quiescent cells

F. Huang, Y. Feng, B. M. Peterlin, K. Fujinaga

This study identifies Siah1/2 as E3 ligases that degrade dissociated CycT1 in resting cells, preventing P-TEFb formation.

bioRxiv · Dec 30, 2021Biochemistry

Assembly and levels of P-TEFb depend on reversiblephosphorylation of cyclinT1

F. Huang, T. N. N. Nguyen, I. Echeverria, R. Ramachandran, D. C. Cary, H. Paculova, A. Sali, A. Weiss, B. M. Peterlin, K. Fujinaga

The paper shows that P-TEFb assembly and levels depend on reversible phosphorylation of cyclinT1 by PKC and dephosphorylation by PP1, leading to P-TEFb disassembly and CycT1 degradation in quiescent and terminally differentiated cells.

bioRxiv · May 25, 2021Biochemistry

HIV-1 Nef and CycK:CDK13 antagonize SERINC5 for optimal viral infectivity

Q. Chai, S. Li, M. K. Collins, R. Li, I. Ahmad, S. F. Johnson, D. A. Frabutt, Z. Yang, X. Shen, L. Sun, J. Hu, J. F. Hultquist, B. M. Peterlin, Y.-H. Zheng

This study identifies CycK:CDK13 as a kinase complex that phosphorylates SERINC5 at S360, enhancing Nef-mediated downregulation and counteracting its antiviral activity.

bioRxiv · May 24, 2021Microbiology