B. P. Hedlund

This study shows a high-carbohydrate diet worsens Clostridioides difficile infection in hamsters by causing prolonged dysbiosis, persistent carriage, and higher mortality compared to a standard diet.

This study identifies two new Asgardarchaeota lineages with methylotrophic metabolism enhanced by genetic code expansions, including selenocysteine and pyrrolysine recoding.

The paper investigates Patescibacteria and DPANN, finding they lack electron transport chains and rely on fermentation, suggesting ancestral adaptations to symbiotic lifestyles.

The paper describes novel hyperthermophilic Aquificae viruses with unique genomic features and proposes a new genus based on their distinct replication strategy and gene-sharing networks.

The paper tracks microbiome changes in wild and tank-acclimated Atlantic horseshoe crabs over time, finding a rapid decline in microbial diversity and an increase in opportunistic pathogens in captivity.

This study shows that a high-fat/high-protein diet worsens C. difficile infection in mice, while a high-carbohydrate diet protects against it.