Author

B. P. Thornton

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Biology Disciplines

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Microbiology· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:fungi (other)· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Thomson· 1 shared E. Bignell· 1 shared H. Muhamadali· 1 shared J. Amich· 1 shared J. Scott· 1 shared K. Hollywood· 1 shared L. Tabernero· 1 shared M. Sueiro-Olivares· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

D. Thomson

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1 paper

Recent·Most cited

MicrobiologybioRxivJun 4, 2020

Targeting methionine synthase in a fungal pathogen causes a metabolic imbalance that impacts cell energetics, growth and virulence

J. Scott, M. Sueiro-Olivares, B. P. Thornton…·J. Amich

This paper identifies methionine synthase as a promising antifungal target by showing its essentiality in Aspergillus fumigatus and validates its druggability using a genetic model of established infections.

DOI 10.1128/mbio.01985-20

fungi (other)metabolomics

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