C. S. Hill

This study shows that N4-hydroxycytidine and its prodrug molnupiravir reduce RNA-virus-induced encephalitis by producing less fit viruses with G-to-A and C-to-U mutations.

This study shows that SGS mutations in SKI prevent its binding to phosphorylated SMAD2/3, leading to SKI stabilization and reduced TGF-β responses.

The paper identifies salt-inducible kinases (SIKs) as regulators of TGFβ-mediated transcriptional and apoptotic responses through pharmacological and genetic approaches.

The paper shows that TGF-β family ligands have distinct signaling dynamics due to differences in receptor localization and internalization, driven by ligand-receptor affinity.