Author

Benjamin W Pruitt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Alejandro ChaveziD· 2 shared George M Church· 2 shared Marcelle Tuttle· 2 shared Brian M Turczyk· 1 shared Christopher D Guzman· 1 shared Collins J Collins· 1 shared Daniel J. Wiegand· 1 shared Dimtry Ter-Ovanesyan· 1 shared

Activity by Year

2014-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersSynthetic Biology

Alejandro ChavezORCID

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2 papers

Recent·Most cited

Synthetic BiologyProceedings of the National Academy of SciencesPeer-reviewedMar 19, 2018

Precise Cas9 targeting enables genomic mutation prevention

Alejandro Chavez, Benjamin W Pruitt, Marcelle Tuttle…·George M Church

This paper introduces a method to tune guide RNA for precise Cas9 targeting, preventing mutations in engineered organisms and demonstrating scalability and robustness across Cas9 variants and environments.

DOI 10.1073/pnas.1718148115

mouseexperimental assay

𝕏 PostBluesky

Synthetic BiologybioRxivDec 20, 2014

Highly-efficient Cas9-mediated transcriptional programming

Alejandro Chavez, Jonathan Scheiman, Suhani Vora…·George M Church

This study develops a highly efficient Cas9-based transcriptional activator, VPR-Cas9, capable of activating multiple genes and promoting neuronal differentiation from iPSCs.

DOI 10.1038/nmeth.3312

humanexperimental assay

𝕏 PostBluesky