Synthetic BiologybioRxiv
Highly-efficient Cas9-mediated transcriptional programming
Alejandro Chavez, Jonathan Scheiman, Suhani Vora…·George M Church
This study develops a highly efficient Cas9-based transcriptional activator, VPR-Cas9, capable of activating multiple genes and promoting neuronal differentiation from iPSCs.
DOI 10.1038/nmeth.3312