Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewed
Metabolite mimicry identifies butyrate analogs with select protective functions in the intestinal mucosa
Alfredo Ornelas, Jacob A. Countess, Ji Yeon Kim…·Sean P. Colgan
This study identifies a butyrate analog, 3-chlorobutyrate, that enhances epithelial barrier formation and is protective in colitis without affecting intestinal stem cells.
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