Author

Alfredo Ornelas

University of Colorado AnschutzORCID 0000-0002-6773-6691Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Alexander S. DowdelliD· 2 shared Sean P. ColganiD· 2 shared Adam J. Berlinberg· 1 shared Andrew Stahly· 1 shared Brandon TrentiD· 1 shared Brenda J. SeymouriD· 1 shared Brendan Allen· 1 shared Brittany Gomez· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Alexander S. DowdellORCID

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2 papers

Recent·Most cited

Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedApr 9, 2026

Metabolite mimicry identifies butyrate analogs with select protective functions in the intestinal mucosa

Alfredo Ornelas, Jacob A. Countess, Ji Yeon Kim…·Sean P. Colgan

This study identifies a butyrate analog, 3-chlorobutyrate, that enhances epithelial barrier formation and is protective in colitis without affecting intestinal stem cells.

3 citationstop 3%

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintOct 13, 2023

Microbiota-dependent indole production is required for the development of collagen-induced arthritis

Brenda J. Seymour, Brandon Trent, Brendan Allen…·Kristine A. Kuhn

This study shows that microbiota-dependent indole production is essential for collagen-induced arthritis development and identifies potential therapeutic targets.

DOI 10.1101/2023.10.13.561693

mousehuman

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