Cancer BiologybioRxivPreprint
Screening of clustered regulatory elements reveals functional cooperating dependencies in Leukemia.
Salima Benbarche, Cécile K Lopez, Eralda Salataj…·Camille Lobry
The paper identifies co-regulated genes in leukemia using CRISPRi screening of super-enhancer regions, showing that combined inhibition of KIT and PDGFRA synergizes to impair leukemia cell growth.