Camille Lobry

This study identifies the pentose phosphate pathway's role in regulating myeloid versus lymphoid lineage specification in hematopoietic stem and progenitor cells through metabolic state-fate mapping.

This study shows human cancer cells can be conditioned to associate an extracellular matrix component with a drug, leading to a memory-like response.

This study shows AML blasts fail to polarize when interacting with healthy stromal cells, and AML-derived stromal cells impair polarization of healthy HSPCs and AML blasts.

This study identifies BIRC5 as a targetable vulnerability in TP53 mutant AML, showing that survivin/IAP inhibitors can overcome therapy resistance.

The paper identifies co-regulated genes in leukemia using CRISPRi screening of super-enhancer regions, showing that combined inhibition of KIT and PDGFRA synergizes to impair leukemia cell growth.