Author

H. Demol

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:protein sequence· 1 Organism:yeast· 1

Frequent Co-Authors

S. Devos· 3 shared B. Schepens· 2 shared C. Lonigro· 2 shared D. Fijalkowska· 2 shared F. Impens· 2 shared J. C. Zavala Marchan· 2 shared J. Neyts· 2 shared K. Boucher· 2 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersMicrobiology

S. Devos

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Yeast-based production platform for potent and stable heavy chain-only antibodies

C. Lonigro, H. Eeckhaut, R. A. Symakani, K. Roose, B. Schepens, K. Sedeyn, A.-S. De Smet, J. C. Zavala Marchan, P. Vanhaverbeke, S. Vanmarcke, K. Claes, S. De Cae, H. Demol, S. Devos, D. Fijalkowska, , N. Callewaert

This paper presents a yeast-based platform for producing stable and potent heavy chain-only antibodies, demonstrating its effectiveness with an anti-SARS-CoV-2 example.

bioRxiv · Mar 4, 2024 · PreprintMicrobiology

High-throughput nano-flow proteomics using a dual-column electrospray source

A. Staes, K. Boucher, S. Dufour, T. M. Maia, E. Timmerman, D. Van Haver, J. Pauwels, H. Demol, J. Vandenbussche, F. Impens, S. Devos

The paper introduces a dual-column electrospray source for nano-flow proteomics to improve throughput while maintaining sensitivity in low-input samples.

bioRxiv · Feb 13, 2024 · PreprintBiochemistry

Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that bind a conserved membrane proximal epitope of the spike

S. De Cae, I. Van Molle, L. van Schie, S. R. Shoemaker, J. Deckers, N. Debeuf, S. Lameire, W. Nerinckx, K. Roose, D. Fijalkowska, S. Devos, A.-S. Desmet, J. C. Zavala Marchan, T. Venneman, G. H. Ghassabeh, , B. Schepens

The paper identifies ultrapotent SARS-CoV-2-neutralizing nanobodies that bind a conserved epitope on the spike protein, showing therapeutic efficacy in hamsters.

bioRxiv · Mar 10, 2023 · PreprintMicrobiology

Immunopeptidomics-based design of highly effective mRNA vaccine formulations against Listeria monocytogenes

R. L. Mayer, R. Verbeke, C. Asselman, I. Aernout, A. Gul, D. Eggermont, K. Boucher, F. Thery, T. M. Maia, H. Demol, R. Gabriels, L. Martens, C. Becavin, S. De Smedt, B. Vandekerckhove, , F. Impens

The paper identifies Listeria monocytogenes epitopes using immunopeptidomics and shows that mRNA vaccines encoding these antigens induce strong immune responses and protection in mice.

bioRxiv · Aug 19, 2022 · PreprintImmunology