Author

R. L. Mayer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

B. Vandekerckhove· 2 shared F. Impens· 2 shared K. Mechtler· 2 shared M. Matzinger· 2 shared A. Gul· 1 shared A. Schmücker· 1 shared A. Valenta· 1 shared B. Menten· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

B. Vandekerckhove

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A high-sensitivity low-nanoflow LC-MS configuration for high-throughput sample-limited proteomics

R. Zheng, M. Matzinger, R. L. Mayer, A. Valenta, X. Sun, K. Mechtler

This paper introduces a high-sensitivity LC-MS setup for sample-limited proteomics, achieving 100 runs/day with 70% MS utilization and identifying ~3,000 protein groups from 250 pg of HeLa protein digest.

bioRxiv · Apr 27, 2023Biochemistry

Wide Window Acquisition and AI-based data analysis to reach deep proteome coverage for a wide sample range, including single cell proteomic inputs

R. L. Mayer, M. Matzinger, A. Schmücker, K. Stejskal, G. Krssakova, F. Berger, K. Mechtler

The paper introduces a workflow combining micro pillar array columns, wide window acquisition, and AI-based search engine to enhance proteome coverage and throughput, particularly for single-cell samples.

bioRxiv · Sep 1, 2022 · PreprintBiochemistry

Immunopeptidomics-based design of highly effective mRNA vaccine formulations against Listeria monocytogenes

R. L. Mayer, R. Verbeke, C. Asselman, I. Aernout, A. Gul, D. Eggermont, K. Boucher, F. Thery, T. M. Maia, H. Demol, R. Gabriels, L. Martens, C. Becavin, S. De Smedt, B. Vandekerckhove, , F. Impens

The paper identifies Listeria monocytogenes epitopes using immunopeptidomics and shows that mRNA vaccines encoding these antigens induce strong immune responses and protection in mice.

bioRxiv · Aug 19, 2022 · PreprintImmunology

Single-cell profiling identifies a spectrum of human unconventional intraepithelial T lineage cells

L. Billiet, L. De Cock, G. Sanchez Sanchez, R. L. Mayer, G. Goetgeluk, S. De Munter, M. Pille, J. Ingels, H. Jansen, K. Weening, E. Pascal, K. Raes, S. Bonte, T. Kerre, N. Vandamme, , B. Vandekerckhove

The paper identifies a spectrum of human unconventional intraepithelial T lineage cells using single-cell RNA sequencing and defines their phenotypic and transcriptomic features.

bioRxiv · May 24, 2022Immunology