BioengineeringbioRxiv
Tuning the sensitivity of genetically encoded fluorescent potassium indicators through structure-guided and genome mining strategies
C. C. Torres Caban, M. Yang, C. Lai…·E. S. Boyden
The paper develops genetically encoded fluorescent potassium indicators with tunable binding affinities through structure-guided design and genome mining, showing varying Kd values in vitro and in cells.
DOI 10.1021/acssensors.1c02201