Cancer BiologybioRxiv
Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential therapeutic vulnerabilities
J. H. Rogers, R. Gupta, J. M. Reyes…·R. E. Rau
This study models IKZF1 lesions in B-ALL to show distinct chemosensitivity patterns and therapeutic vulnerabilities, identifying cytarabine sensitivity and JAK/STAT upregulation as potential targets.
DOI 10.1182/bloodadvances.2020002408