The Resolvin D2-GPR18 Axis Enhances Bone Marrow Function and Limits Hepatic Fibrosis in Aging
H. Fitzgerald, J. L. Bonin, S. Sadhu, M. Lipscomb, N. Biswas, C. Decker, M. Nabage, R. Bossardi, M. Marinello, A. Hebe Mena, K. Gilliard, M. Spite, A. Adam, K. C. MacNamara, G. Fredman
This study shows that RvD2-GPR18 signaling reduces hepatic fibrosis and steatosis in aging by enhancing bone marrow function and macrophage populations.
bioRxiv · Jan 5, 2023 · PreprintPhysiology