H2O2 mediated MAPK-mTOR crosstalk determines the XIAP and FLIP degradation pathways and development of resistance to Imatinib
R. Roy, T. Paul, S. Sinha, N. Biswas
This study shows H2O2-mediated mTOR activation determines protein degradation pathway and Imatinib resistance in K562 cells.
bioRxiv · Apr 28, 2024 · PreprintCancer Biology