Author

C. Dela Sena

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

M. Schapira· 2 shared M. Vedadi· 2 shared A. Allali-Hassani· 1 shared A. Dong· 1 shared A. Iqbal· 1 shared A. Yudin· 1 shared B. M. Watson· 1 shared C. A. Zepeda-Velazquez· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

M. Schapira

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintDec 4, 2020

A First-in-class, Highly Selective and Cell-active AllostericInhibitor of Protein Arginine Methyltransferase 6 (PRMT6)

Y. Shen, F. Li, M. Szewczyk…·J. Jin

This paper reports the discovery of a first-in-class, highly selective allosteric inhibitor of PRMT6, SGC6870, with potent activity and selectivity in vitro and in cells.

DOI 10.1101/2020.12.04.412569

experimental assaydrug response / drug discovery

𝕏 PostBluesky

Pharmacology & ToxicologyBioorganic & Medicinal ChemistryPeer-reviewedSep 1, 2019

Identification and Characterization of the First Fragment Hits for SETDB1 Tudor Domain

P. Mader, R. Mendoza-Sanchez, A. Iqbal…·C. Arrowsmith

The paper identifies small molecule fragments that bind to the tudor domain of SETDB1 and describes their binding modes and biophysical properties.

DOI 10.1016/j.bmc.2019.07.020

humanprotein structure

𝕏 PostBluesky