BiochemistrybioRxiv
Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein
X. Chen, Y. Ali, C. E. L. Fisher…·A. W. Oliver
The paper identifies an allosteric inhibitor of BLM's ATPase-coupled DNA helicase activity and characterizes its mechanism through crystallographic analysis.
DOI 10.7554/elife.65339