Author

C. G. Tate

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Assay:cryo-EM· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Dore· 1 shared A. G. W. Leslie· 1 shared B. Carpenter· 1 shared J. Garcia-Nafria· 1 shared P. Edwards· 1 shared T. Warne· 1 shared X. Bai· 1 shared Y. Lee· 1 shared

Activity by Year

2018-2018 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 12 mutual co-author links

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1 shared paperBiochemistry

A. Dore

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2 papers

Recent·Most cited

BiochemistrybioRxivOct 5, 2018

Molecular basis for high affinity agonist binding in GPCRs

T. Warne, P. Edwards, A. Dore…·C. G. Tate

The paper determines active-state structures of β1AR bound to agonists and identifies structural changes that increase agonist affinity.

DOI 10.1126/science.aau5595

structural biologyexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivFeb 19, 2018

Cryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein

C. G. Tate, J. Garcia-Nafria, Y. Lee…·B. Carpenter

The paper determines the cryo-EM structure of the adenosine A2A receptor bound to NECA and coupled to an engineered G protein, revealing structural similarities and flexibility compared to a crystal structure.

DOI 10.7554/elife.35946

cryo-EMexperimental assay

𝕏 PostBluesky