Author

C. Gharsallah

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

E. Prina· 2 shared G. F. Spaeth· 2 shared H. Lecoeur· 2 shared H. Varet· 2 shared R. Legendre· 2 shared A. A. Baniahmad· 1 shared A. Bruckmann· 1 shared A. Mai· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMicrobiology

E. Prina

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

MAPPING CHANGES OF MIRNA-MRNA NETWORKS IN LEISHMANIA-INFECTED MACROPHAGES PREDICTS REGULATORY MIRNA-TF LOOPS AS NOVEL TARGETS OF PARASITE IMMUNE SUBVERSION

C. Gharsallah, H. Lecoeur, H. Varet, R. Legendre, O. Sismeiro, J.-Y. Coppee, C. Proux, E. Scarfiello, A. Bruckmann, G. Meister, E. Prina, G. F. Spaeth

bioRxiv · Mar 24, 2024 · PreprintMicrobiology

Inhibition of the macrophage demethylase LSD1 reverses Leishmania amazonensis-induced transcriptomic changes and causes a decrease in parasite load

M. Gutierrez-Sanchez, A. A. Baniahmad, C. Gharsallah, S. Zhang, S. Lamotte, K. Schmidtkunz, H. Varet, R. Legendre, N. Traves, F. Dingli, D. Loew, D. Rotili, S. Valente, A. Mai, P. Loiseau, , G. F. Spaeth

This study shows that inhibiting LSD1 in macrophages reduces Leishmania parasite load and reverses infection-induced transcriptomic changes.

bioRxiv · Sep 29, 2023 · PreprintCell Biology