BiochemistrybioRxiv
A hold-and-feed mechanism drives directional DNA loop extrusion by condensin
I. A. Shaltiel, S. Datta, L. Lecomte…·C. H. Haering
This study reveals that condensin uses a hold-and-feed mechanism to extrude DNA loops bidirectionally by separating motor and anchor functions in distinct chambers.
DOI 10.1126/science.abm4012