Author

C. Hachicho

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

C. L. Vizcarra· 2 shared A. G. Carl· 1 shared A. Klestzick· 1 shared A. Oza· 1 shared C. M. Rojas· 1 shared D. E. Wilcox· 1 shared D. Nambiar· 1 shared F. Bartolini· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

C. L. Vizcarra

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Metallothionein-3 attenuates the effect of Cu2+ ions on actin filaments

R. Lakha, C. Hachicho, M. R. Mehlenbacher, D. E. Wilcox, R. N. Austin, C. L. Vizcarra

This study shows that MT-3 does not directly bind actin but reduces Cu2+-induced actin filament fragmentation by chelating Cu2+.

bioRxiv · Sep 23, 2022Biochemistry

Actin nucleotide state modulates the F-actin structural landscape evoked by bending forces

M. J. Reynolds, C. Hachicho, A. G. Carl, R. Gong, G. M. Alushin

This study shows bending forces induce structural changes in F-actin that depend on its nucleotide state, with phosphate stabilizing subunit conformations and altering the structural landscape.

bioRxiv · Jun 2, 2022Biophysics

Alterations to the broad-spectrum formin inhibitor SMIFH2 improve potency

M. Orman, M. Landis, A. Oza, D. Nambiar, J. Gjeci, K. Song, V. Huang, A. Klestzick, C. Hachicho, S. Q. Liu, J. M. Kamm, F. Bartolini, J. J. Vadakkan, C. M. Rojas, C. L. Vizcarra

The paper tests SMIFH2 and its derivatives against human formins, finding that modifications enhance potency but do not allow distinction between conserved FH2 domains.

bioRxiv · Mar 10, 2022 · PreprintBiochemistry