Author

A. Crane

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Paleontology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Bafica· 1 shared A. Chen· 1 shared A. Gurkar· 1 shared A. Parise· 1 shared A. Parwal· 1 shared A. W. Grande· 1 shared B. Kim· 1 shared B. Raught· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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1 shared paperImmunology

A. Bafica

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Taphonomic damage obfuscates interpretation of the retroarticular region of the Asteriornis mandible

A. Crane, J. Benito, A. Chen, G. Musser, C. R. Torres, J. A. Clarke, S. Lautenschlager, D. T. Ksepka, D. J. Field

The paper reinterprets the retroarticular region of Asteriornis mandible, showing taphonomic damage obscured its morphology, and updates phylogenetic analysis to support its placement as a total-group galloanseran.

bioRxiv · Jun 13, 2023 · PreprintPaleontology

Aberrant DNA repair is a vulnerability in histone H3.3-mutant brain tumors

B. Rondinelli, G. Giacomini, S. Piquet, O. Chevallier, J. Dabin, S.-K. Bai, B. Kim, R. Siddaway, B. Raught, E. Coyaud, C.-M. Shan, R. J. D. Reid, T. Toda, R. Rothstein, T. Wilhelm, , S. E. Polo

The paper identifies aberrant DNA repair as a vulnerability in H3.3-mutant brain tumors, showing that PNKP-mediated repair is specific to mutant cells and offers therapeutic potential.

bioRxiv · Sep 29, 2022 · PreprintCancer Biology

Non-canonical Telomerase Reverse Transcriptase Controls Osteogenic Reprogramming of Aortic Valve Cells Through STAT5

R. A. Cuevas, L. Hortells, C. Chu, R. Wong, A. Crane, C. Boufford, C. Regan, W. Moorhead, M. Bashline, A. Parwal, A. Parise, P. Behzadi, A. Gurkar, D. Bruemmer, J. Sembrat, , C. St. Hilaire

This study identifies TERT's non-canonical role in osteogenic reprogramming of aortic valve cells through STAT5, offering a potential therapeutic target for calcific aortic valve disease.

bioRxiv · Aug 23, 2022Pathology

Zika virus-based immunotherapy enhances long-term survival of rodents with brain tumors through upregulation of memory T-cells

A. Crane, M. R. Chrostek, V. D. Krishna, M. Shiao, N. G. Toman, C. M. Pearce, S. K. Tran, C. J. Sipe, W. Guo, J. P. Voth, S. Vaid, H. Xie, W.-C. Lu, W. Swanson, A. W. Grande, , W. C. Low

This study shows that Zika virus-based immunotherapy improves long-term survival in mice with brain tumors by boosting memory T-cell levels.

PLOS ONE · Oct 1, 2020Peer-reviewedCancer Biology

Vasculature-associated adipose tissue macrophages dynamically adapt to inflammatory and metabolic challenges

H. Moura Silva, A. Bafica, G. F. Rodrigues-Luiz, J. Chi, P. d. A. Santos, B. Sgarbi Reis, D. Hoytema van Konijnenburg, A. Crane, R. D. N. Arifa, P. Martin, D. A. Gasparin Bueno Mendes, D. S. Mansur, V. Torres, K. Cadwell, P. Cohen, , J. J. Lafaille

The paper identifies vasculature-associated adipose tissue macrophages (VAMs) and shows how they adapt to metabolic and inflammatory challenges in epididymal white adipose tissue.

bioRxiv · May 31, 2018Immunology