C. Hierro-Yap

This study shows that Trypanosoma brucei mitochondria can produce ATP via substrate phosphorylation, which is crucial under nutrient-limited conditions.

This paper demonstrates that MitoTam, a mitochondria-targeted tamoxifen analog, effectively kills various pathogens including fungi, Plasmodium falciparum, and trypanosomatid parasites in vitro and in vivo.

This study shows that depletion of cardiolipin in Trypanosoma brucei bloodstream forms disrupts mitochondrial function and energy metabolism, leading to reduced ATP levels and altered metabolic pathways.