Plasmodium falciparum-specific IgM B cells dominate in children, expand with malaria and produce parasite inhibitory IgM
C. Hopp, A. Diouf, K. Miura, K. Boswell, P. Sekar, J. Skinner, C. M. Tipton, M. Chambers, S. Andrews, J. Tan, S. Li, S. Doumbo, K. Kayentao, A. Ongoiba, B. Traore, , P. D. Crompton
The paper identifies Pf-specific IgM B cells in children, showing they expand during malaria and produce inhibitory IgM antibodies.
bioRxiv · Apr 12, 2020Immunology